- NSB was founded in 1541 by Thomas Chipsey, who served as mayor of Northampton several times, and whose fellow trustees included Lawrence Washington, an ancestor of George Washington, the first president of the United States.
- Multimillion-pound investments include an indoor swimming centre, a dance facility and a refurbished theatre and music department.
- Pupils have reached the national finals in several sports, and an NSB team has won the U15 England rugby title.
- Students at Northampton School, an 11-16 free school that opened in 2023, gain an automatic place in NSB’s coeducational sixth form, subject to entry requirements.
- Northampton School for Boys was awarded Comprehensive School of the Year in the East Midlands 2025
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